| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Hyper-IgE syndrome v1.3 | IL6ST | Zornitza Stark Marked gene: IL6ST as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.3 | IL6ST | Zornitza Stark Gene: il6st has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.3 | IL6ST | Zornitza Stark Phenotypes for gene: IL6ST were changed from Dominant Negative Hyper IgE syndrome to Hyper-IgE recurrent infection syndrome 4A, autosomal dominant , MIM#619752; Hyper-IgE recurrent infection syndrome 4B, autosomal recessive, MIM# 618523 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.2 | IL6ST | Zornitza Stark Publications for gene: IL6ST were set to PMID: 32207811 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.2 | IL6ST | Zornitza Stark Mode of inheritance for gene: IL6ST was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to BOTH monoallelic and biallelic, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.1 | IL6ST | Zornitza Stark Classified gene: IL6ST as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.1 | IL6ST | Zornitza Stark Gene: il6st has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.0 | IL6ST | Zornitza Stark reviewed gene: IL6ST: Rating: GREEN; Mode of pathogenicity: None; Publications: 33771552, 30309848, 28747427, 32207811; Phenotypes: Hyper-IgE recurrent infection syndrome 4A, autosomal dominant , MIM#619752, Hyper-IgE recurrent infection syndrome 4B, autosomal recessive, MIM# 618523; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hyper-IgE syndrome v1.0 | IL6ST |
Peter McNaughton gene: IL6ST was added gene: IL6ST was added to Hyper-IgE syndrome. Sources: Literature Mode of inheritance for gene: IL6ST was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: IL6ST were set to PMID: 32207811 Phenotypes for gene: IL6ST were set to Dominant Negative Hyper IgE syndrome Penetrance for gene: IL6ST were set to unknown Mode of pathogenicity for gene: IL6ST was set to Other Review for gene: IL6ST was set to GREEN Added comment: Sources: Literature |
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