| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Incidentalome v0.61 | NTHL1 | Zornitza Stark Marked gene: NTHL1 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Incidentalome v0.61 | NTHL1 | Zornitza Stark Gene: nthl1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Incidentalome v0.61 | NTHL1 | Zornitza Stark Classified gene: NTHL1 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Incidentalome v0.61 | NTHL1 | Zornitza Stark Gene: nthl1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Incidentalome v0.60 | NTHL1 |
Zornitza Stark gene: NTHL1 was added gene: NTHL1 was added to Incidentalome. Sources: Literature Mode of inheritance for gene: NTHL1 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: NTHL1 were set to 33454955 Phenotypes for gene: NTHL1 were set to NTHL1-associated cancer syndrome Review for gene: NTHL1 was set to GREEN Added comment: More than 10 unrelated families reported with a hereditary cancer syndrome predisposing to adenomatous polyposis and colorectal cancer. Half of biallelic carriers also displayed multiple colonic or extra-colonic primary tumors, mainly breast, endometrium, urothelium, and brain tumours. For digestive cancers, average age at diagnosis was 56.2 years. Sources: Literature |
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