| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Early-onset Dementia v0.25 | TAF15 | Bryony Thompson Classified gene: TAF15 as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Dementia v0.25 | TAF15 | Bryony Thompson Gene: taf15 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Dementia v0.12 | TAF15 |
Bryony Thompson gene: TAF15 was added gene: TAF15 was added to Early-onset Dementia. Sources: Expert list Mode of inheritance for gene: TAF15 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: TAF15 were set to 28889094 Phenotypes for gene: TAF15 were set to Amyotrophic lateral sclerosis; Frontotemporal dementia Review for gene: TAF15 was set to AMBER Added comment: Two missense variants identified in two unrelated cases with a similar phenotype which included low motor neuron predominant signs, behavioural variant FTD and movement disorders, and in one patient, neuropathology showed a frontotemporal lobar degeneration pattern. Sources: Expert list |
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