| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Early-onset Dementia v0.221 | TIA1 | Bryony Thompson Marked gene: TIA1 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Dementia v0.221 | TIA1 | Bryony Thompson Gene: tia1 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Dementia v0.221 | TIA1 | Bryony Thompson Classified gene: TIA1 as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Dementia v0.221 | TIA1 | Bryony Thompson Gene: tia1 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Dementia v0.220 | TIA1 |
Bryony Thompson gene: TIA1 was added gene: TIA1 was added to Early-onset Dementia. Sources: Literature Mode of inheritance for gene: TIA1 was set to Other Publications for gene: TIA1 were set to 36861178; 29599744; 29457785 Phenotypes for gene: TIA1 were set to Multisystem proteinopathy Review for gene: TIA1 was set to AMBER Added comment: Digenic variants in SQSTM1 and TIA1 have been reported in multisystem proteinopathy which includes clinical combinations of inclusion body myopathy (IBM), neurodegeneration [motor neuron disorder (MND)/frontotemporal dementia (FTD)], and Paget disease of bone (PDB). FTD has reported in at least one individual with FTD as a feature of the phenotype. Sources: Literature |
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