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| Osteogenesis Imperfecta and Osteoporosis v0.57 | WNT4 |
Bryony Thompson gene: WNT4 was added gene: WNT4 was added to Osteogenesis Imperfecta. Sources: Expert list Mode of inheritance for gene: WNT4 was set to Unknown Publications for gene: WNT4 were set to 25108526; 26733379 Phenotypes for gene: WNT4 were set to Osteoporosis Review for gene: WNT4 was set to RED Added comment: Mouse model where recombinant Wnt4 alleviated bone loss and inflammation by inhibiting NF-κB in vivo in mouse models of bone disease. However, no reported association with Mendelian disease. A common SNP (rs10917157) has been associated with bone mineral density. Sources: Expert list |
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