SIM1

single-minded family bHLH transcription factor 1
OMIM: 603128, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Green SIM1 in Mendeliome


Version 1.1902

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • congenital obesity
  • Prader-Willi-like syndrome

Red SIM1 in Fetal anomalies


Version 1.255

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • Genomics England PanelApp
Phenotypes
  • Severe obesity with neurobehavioral features

Green SIM1 in Severe early-onset obesity


Level 2: Endocrine disorders
Version 1.10

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Genomics England PanelApp
Phenotypes
  • congenital obesity
  • Prader-Willi-like syndrome